Ozcanium Chemical Supplies
Retatrutide 10mg 99.45 HPLC Tested
Retatrutide 10mg 99.45 HPLC Tested
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Retatrutide (LY3437943) | 10mg lyophilized peptide
Analytical Grade ≥ 99 % purity (HPLC)
Properties:
| CAS | 2381089-83-2 |
|---|---|
| IUPAC | |
| Formula / Mr | C221H342N46O68 · 4731 g mol-1 |
| Target | Triple agonist: GLP-1R / GIPR / GCGR (tri-incretin/glucagon) |
Mechanism & pre-clinical highlight:
Retatrutide is a lipidated “unimolecular polypharmacology” peptide designed to activate GIP, GLP-1, and glucagon receptors, aiming to combine appetite/energy-intake reduction (GLP-1/GIP) with increased oxidative metabolism/energy expenditure signals (glucagon). Its pharmacokinetics support once-weekly dosing (half-life ≈ 6 days). In a randomized Phase 2 trial in adults with obesity, 48 weeks of once-weekly retatrutide produced dose-dependent weight loss, reaching ~24.2% mean reduction at the highest dose, with improvements in multiple cardiometabolic markers; the most common adverse events were gastrointestinal (e.g., nausea/diarrhea), consistent with incretin-based therapies.
Handling & storage
Store sealed, dry, dark, 15 – 25 °C.
Disclaimer
For laboratory research use only – not for human or veterinary use. Use appropriate PPE; consult SDS before handling. Ozcanium Chemical Supplies/Ozcanium Analytics assumes no liability for misuse, improper handling, or non-compliant application of this material.
